Top 25 Overall
The following rankings in no way are an indication of what round or position a player will be drafted. It is only a comparison of players at all positions to determine overall value. These rankings are determined by Draft Breakdown through their own observations, scouting reports and information obtained through contacts throughout the draft community. The following rankings are also subject to change until shortly before the draft, at which point a final top 100 ranking will be posted.
| 1. | Jake Locker | QB | Washington |
| 2. | Adrian Clayborn | DE | Iowa |
| 3. | Cameron Heyward | DT | Ohio State |
| 4. | Prince Amukamara | CB | Nebraska |
| 5. | Marvin Austin | DT | North Carolina |
| 6. | Allen Bailey | DE | Miami |
| 7. | Bruce Carter | OLB | North Carolina |
| 8. | Von Miller | OLB | Texas A&M |
| 9. | Greg Romeus | DE | Pittsburgh |
| 10. | Anthony Castonzo | OT | Boston College |
| 11. | Greg Jones | ILB | Michigan State |
| 12. | Christian Ponder | QB | Florida State |
| 13. | DeMarco Murray | RB | Oklahoma |
| 14. | Ras-I Dowling | CB | Virginia |
| 15. | Daniel Thomas | RB | Kansas State |
| 16. | Stephen Paea | DT | Oregon State |
| 17. | Mark Herzlich | OLB | Boston College |
| 18. | Jerrell Powe | DT | Ole Miss |
| 19. | DeAndre McDaniel | SS | Clemson |
| 20. | Gabe Carimi | OT | Wisconsin |
| 21. | Stefan Wisniewski | C | Penn State |
| 22. | Quan Sturdivant | ILB | North Carolina |
| 23. | Rodney Hudson | OG | Florida State |
| 24. | Mike Pouncey | C | Florida |
| 25. | Deunta Williams | FS | North Carolina |
* list only includes Senior prospects
